Tries from Carl Fearns, Mickael Ivaldi and Thibaut Regard helped Lyon get back to winning ways in Saturday's Top 14 action.
A 28-9 victory over Stade Francais saw Top 14 leaders Toulouse break a league record as they extended their unbeaten run to 12 games.
Perpignan finally had a win to celebrate, while Clermont Auvergne were too good for Bordeaux-Begles in Top14.
Clermont Auvergne made the most of a chaotic spell in which Racing 92 were reduced to 13 men, triumphing in Top 14 on Sunday.
Sergio Parisse was shown a red card in the first half, but Stade Francais made a winning start to the Top 14 away at newly-promoted Perpignan.