lang-eng Five Six Nations changes for Wales, including a new cap on the wing
The Welsh were well beaten 5-36 last Saturday by Ireland in Cork and the response has been to alter four of the backline and one of the pack.
The England duo of Joe Marler and Danny Care will not feature for Harlequins in the Investec Champions Cup quarter-final against Bordeaux-Begles on Saturday, with director of rugby Billy Millard opting to rest them.